Multidrug resistance-associated protein

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August undefined, 2024

Multidrug resistance-associated protein 2 (MRP2) also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 (ABCC2) is a protein that in humans is encoded by the ABCC2 gene. Web4 apr. 2006 · There are now nine members of the multidrug resistance-associated protein family and eight of these (MRP1–8) are known to be organic anion transporters. Between them, the MRPs can transport a large range of organic anions, including anionic drugs and drugs conjugated to glutathione (GSH), sulfate, or glucuronate.

Targeting multidrug resistance-associated protein 1 …

Web15 apr. 2015 · The efflux transporters including P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 2 (MRP2) … Web10 aug. 2011 · Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC … gresstrimmer clas ohlson

Multidrug Resistance Associated Protein - an overview

Webresistance [re-zis´tans] 1. opposition, or counteracting force, as opposition of a conductor to passage of electricity or other energy or substance. 2. the natural ability of a normal … Web21 oct. 2024 · Summary encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. An ABCC-type arsenite-phytochelatin transporter. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim. Other designations multidrug resistance-associated protein 2 WebFrom the structural point of view, only the bovine ortholog of the multidrug-resistance associated protein 1 (bMRP1) has been resolved. We here used ms-scaled molecular dynamics simulations to investigate the structure and dynamics of bMRP1 in pre- and post-hydrolysis functional states. The present work aims to examine the slight but likely ... gress trucking milan il

ABCC2 multidrug resistance-associated protein 2 [ (thale cress)]

WebAcum 2 zile · Antibiotic resistance (AR) is posing a serious threat to the global health. By accumulating intrinsic resistant mutations or horizontally transferred AR genes, bacteria can evolve to be... WebMultidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together … gress taxWebABCC1 protein (human) - STRING interaction network Nodes: Network nodes represent proteins splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus. Node Color colored nodes: query proteins and first shell of interactors white nodes: fics install page - 푸디스트

"WebThe phytoestrogen resveratrol has putative health-promoting effects and is present in several dietary constituents. Resveratrol is metabolized extensively in t " - Multidrug resistance-associated protein

Multidrug resistance-associated protein

WebMultidrug resistance-associated protein 1 (MRP1/ABCC1) has been shown to cause multidrug resistance in model cell lines and in clinical settings. We explored the … WebFrom the structural point of view, only the bovine ortholog of the multidrug-resistance associated protein 1 (bMRP1) has been resolved. We here used ms-scaled molecular …

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WebMRP1 is found not only in the plasma membrane associated with lipid rafts but also in cytoplasmic accumulations colocalizing with the prostasome markers Caveolin-1 and CD59, suggesting that in CaP cells, MRP1 is localized in prostasomes.Conclusion: We hypothesize that the presence of MRP1 in prostasomes could serve as a reservoir of MRP1; thus ... WebMultidrug resistance protein 1 and multidrug resistance-associated protein 1 are transporters that efflux diverse xenobiotics from cells. We investigated changes in the expression and activity of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in highly purified lung dendritic cells (LDCs) during aging using …

Web* P<0.05. miR, microRNA; VCR, vincristine; ADM, adriamycin; miR-NC, scramble control; MDR1/P-gp, multidrug resistance protein 1/P-glycoprotein; MRP-1, multidrug … WebMultidrug resistance protein 4 (Mrp4) is an efflux transporter known to transport several xenobiotics and endogenous molecules. We recently identified that the lack of Mrp4 …

WebMRP1 is found not only in the plasma membrane associated with lipid rafts but also in cytoplasmic accumulations colocalizing with the prostasome markers Caveolin-1 and … Web1 mai 2024 · As depicted in Table 2, phenotypically, majority of the isolates were recorded as multidrug resistance (MDR) as they were recorded as resistant to three or more than three classes of antibiotics. Maximum resistance was …

WebAcum 2 zile · Antibiotic resistance (AR) is posing a serious threat to the global health. By accumulating intrinsic resistant mutations or horizontally transferred AR genes, bacteria …

ficshcWeb25 iun. 1996 · A Saccharomyces cerevisiae strain with a disrupted yeast cadmium resistance factor (YCF1) gene (DTY168) is hypersensitive to cadmium. YCF1 … gress on the microwaveWeb6 dec. 1999 · The human multidrug resistance protein (MRP) family contains at least six members: MRP1, the godfather of the family and well known as the multidrug … gresswell book cleanerWebMultidrug resistance protein 1 and multidrug resistance-associated protein 1 are transporters that efflux diverse xenobiotics from cells. We investigated changes in the … fic/signWebMultidrug-resistance proteins (MRPs) belong to the superfamily of ABC transporters, have the ability of transporting a wide range of endo and xenobiotics [80]. The MRPs family … fics interativasWeb18 mai 2010 · Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:9281595). … ficsisWebMultidrug Resistance-Associated Protein 3 MRP3 (ABCC3) is a member of the ABC protein superfamily of transporters. 122 It serves a unique role in the hepatic response … gresswell book supports