Oxathiolane
WebNational Center for Biotechnology Information WebBackground: T-705 (Favipiravir) is a broad spectrum antiviral agent approved for stockpiling in Japan and currently in Phase 3 testing in the United States. Against …
Oxathiolane
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WebObjective: To develop new analogs, a class of 1,3-oxathiolane nucleoside derivatives of T-705 was designed and synthesized in this work. Results: Anti-influenza activity and Anti-HIV activity of these compounds were evaluated. Compound 1a displayed activity against A H1N1 with an IC50 of 40.4 µmol/L. Compound 1b showed weak activity against ... WebTraductions en contexte de "guloses" en anglais-français avec Reverso Context :
Web1,2-Oxathiolane, 2,2-dioxide Formula: C 3 H 6 O 3 S Molecular weight: 122.143 IUPAC Standard InChI: InChI=1S/C3H6O3S/c4-7 (5)3-1-2-6-7/h1-3H2 IUPAC Standard InChIKey: … Weboxathiolane noun A five-membered saturated heterocycle having a three carbon atoms, one oxygen atom and one sulfur atom How to pronounce oxathiolane? David US English Zira …
WebMar 11, 2009 · The X-ray structure of major trans diastereomer of 2-phenyl-4-isobutyl-1,3-oxathiolane S,S-dioxide shows an envelope conformation with oxygen at the flap and an internal angle at sulfur of just 93 ... WebA stereoselective large-scale synthetic process is described to produce 1,3-oxathiolane nucleoside, lamivudine. A mild, inexpensive, and readily available zirconium (IV) chloride (ZrCl 4) catalyst acts as a substrate activator for the key N-glycosylation step at room temperature.An optimum of 0.5 equiv of ZrCl 4 is required, which gives encouraging …
WebApr 29, 2024 · What is claimed is: 1. A method of inhibiting or partially inhibiting activity of one or more PIM (proviral integration site for Moloney murine leukemia virus) kinase(s) comprising contacting a PIM kinase with a compound of Formula (I) or Formula (II) or a pharmaceutically acceptable salt, solvate, hydrate, or N-oxide, prodrug, or isotopic …
WebCompound 1,3-Oxathiolanewith free spectra: 4 NMR, and 5 MS. KnowItAll Campus Solutions. KnowItAll offers faculty and students at your school access to all the tools you need for spectral analysis and structure drawing & publishing! hardware store rochester nhWebSep 15, 2014 · The reactions including 1,3-oxathiolane intermediates and heterobicyclo[2.2.1]heptane transition states can be initiated by two ways. For the first way, methanolysis of 5-acyloxymethyl substituted 1,3-oxathiolane-2-imine (Scheme 1) gives corresponding alkoxide ion OT-a,b (Fig. 1, Fig. 2; Scheme 4, Scheme 5) or a zwitterion OT … hardware store rockmart gaWebThe present invention provides compounds and intermediates. The present invention also provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation. The present invention also provides compounds that may be used as synthetic intermediates in the … hardware store round rockWeb1,2-Oxathiolane 2,2-dioxide, 3-Hydroxypropanesulfonic acid γ-sultone Empirical Formula (Hill Notation): C3H6O3S CAS Number: 1120-71-4 Molecular Weight: 122.14 Beilstein: 109782 … hardware store rocky hill ctWebThe kinetics of 1,3-oxathiolane-2-thione synthesis are determined, and the resulting rate equation, along with a stereochemical analysis of the reaction and catalyst modification studies, is used to determine a mechanism for the synthesis of 1,3-oxathiolane-2-thiones which contrasts with the mechanism previously determined for cyclic carbonate ... change outlook user accountWeb一站式科研服务平台. 学术工具. 文档翻译; 收录引证; 论文查重; 文档转换 change outlook user informationWebProduct Name: 5-phenyl-1,3-oxathiolane-2-thione CAS Number: 86972-18-1 EINECS: Molecular Weight: 196.294 Molecular Formula: C9H8OS2 HS Code: Mol File: 86972-18-1.mol Synonyms: 5-phenyl-1,3-oxathiolane-2-thione Post Buying Request Now Navigation Chemical Properties Safety information and MSDS Supplier and reference price hardware store ruston la